How NAD+ Supports Cellular Energy and Longevity
NAD+

How NAD+ Supports Cellular Energy and Longevity

Published 2025-12-18 • 2 min read
Discover how NAD+ plays a crucial role in cellular metabolism, DNA repair, and healthy aging. Learn why NAD+ levels decline with age and how supplementation can help restore vitality.

What Is NAD+ and Why Does It Matter?

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in every cell of your body. It plays a fundamental role in energy production, DNA repair, and cellular communication. As we age, NAD+ levels naturally decline, which researchers believe contributes to many age-related health challenges.

NAD+ is essential for mitochondrial function—the powerhouses of your cells. Without adequate NAD+, your cells struggle to produce the energy needed for optimal function. This can manifest as fatigue, reduced mental clarity, and decreased physical performance.

The Science Behind NAD+ Decline

Research shows that NAD+ levels drop by approximately 50% between ages 40 and 60. This decline affects multiple bodily systems simultaneously. Your cells require NAD+ to activate sirtuins, a family of proteins that regulate cellular health and longevity.

Several factors accelerate NAD+ depletion including chronic stress, poor sleep, excessive alcohol consumption, and a diet high in processed foods. Environmental toxins and UV radiation also consume NAD+ as your body works to repair cellular damage.

Benefits of NAD+ Supplementation

Restoring NAD+ levels through supplementation may support numerous aspects of health and wellness. Many users report increased energy levels, improved mental clarity, and better exercise recovery. Some research suggests NAD+ supplementation may support healthy aging at the cellular level.

NAD+ therapy has gained attention in the longevity and functional medicine communities. Studies indicate potential benefits for metabolic health, cardiovascular function, and neuroprotection. While research is ongoing, early results are promising.

Energy and Metabolism

NAD+ is directly involved in converting food into usable energy. Higher NAD+ levels may support more efficient metabolism and sustained energy throughout the day. Many users notice reduced afternoon fatigue and more consistent performance.

Cognitive Function

Your brain is one of the most energy-demanding organs in your body. Adequate NAD+ levels support neuronal energy production and may help maintain cognitive function. Some research suggests NAD+ plays a role in protecting brain cells from age-related decline.

Choosing Your NAD+ Delivery Method

Serena Health offers two effective NAD+ delivery options: NAD+ Injectable ($299/month) and NAD+ Nasal Spray ($199/month). Injectable provides maximum bioavailability for those seeking the most potent effects. Nasal spray offers convenience and ease of use for daily maintenance.

Both options bypass the digestive system, ensuring optimal absorption. Your choice depends on your goals, preferences, and lifestyle. Many patients start with injectable therapy and transition to nasal spray for maintenance.

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Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with a healthcare professional before starting any new supplement regimen.

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